Health news

Differences in comorbidities and associated severity and mortality among individuals with COVID-19

This systematic review and meta-analysis aimed to determine geographical, age, and gender related differences in the prevalence of comorbidities and associated severity and mortality rates among COVID-19 patients. Of 120 studies with 125,446 patients, the most prevalent comorbidities were hypertension (32%), obesity (25%), diabetes (18%) and cardiovascular disease (16%). Chronic kidney or other renal diseases (51%), cerebrovascular accident (43%), and cardiovascular disease (44%) patients had more COVID-19 severity and mortality respectively. Considerable variation in the prevalence of comorbidities and associated disease severity and mortality in different geographic regions was observed.

New guideline (UK): SARS-CoV-2 routes of transmission and recommendations for preventing acquisition

This guidance document was co-produced by a multi-professional group including clinicians, nurses, academics, and a member of the public. It provides current evidence regarding routes of SARS-CoV-2 transmission and offers recommendations to assist frontline health professionals and managers.

The efficacy and safety of paracetamol for pain relief

An analysis of 36 systematic reviews of randomised controlled trials recently published in the MJA, identified just four conditions for which there was high or moderate quality evidence that paracetamol relieved pain – knee or hip osteoarthritis, craniotomy, tension-type headaches, and perineal pain after childbirth. However even then, the size of pain reduction is small. The study found high quality evidence that paracetamol is not effective for relieving acute low back pain. Frequency of adverse events was generally similar for people receiving placebo or paracetamol.
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Patients’ experience of severe asthma add-on therapies

This study from the Department of Respiratory & Sleep Medicine at JHH, provides insight into the patient’s experience of add-on therapies for severe asthma. Understanding these experiences will aid communication of the potential benefits and limitations of these add-on medications. They can also guide discussion around alternative treatment in cases of reduced treatment efficacy or non-response.

Previous health news

Due to budget constraints the Library Service hasn’t been able to renew the following subscriptions for 2021.

  • Age and ageing (OUP)
  • Annals of the rheumatic diseases (BMJ)
  • Archives of disease in childhood (BMJ)
  • BJR: British journal of radiology (Wiley)
  • BMJ Case reports
  • BMJ Evidence-based medicine
  • BMJ Supportive & palliative care
  • British journal of anaesthesia (Elsevier)
  • Chest (Elsevier)
  • Clinical infectious diseases (OUP)
  • European heart journal (OUP)
  • Evidence based nursing (BMJ)
  • Heart (BMJ)
  • International journal of gynecological cancer (BMJ)
  • Joint Commission Journal on quality and patient safety (Elsevier)
  • Journal of clinical pathology (BMJ)
  • Journal of medical ethics (BMJ)
  • Journal of medical genetics (BMJ)
  • Journal of neurology, neurosurgery & psychiatry (BMJ)
  • Journal of oral and maxillofacial surgery (Elsevier)
  • Journal of telemedicine and telecare (Sage)
  • Journal of the American College of Cardiology (Elsevier)
  • Journal of the National Cancer Institute (OUP)
  • Journal of thoracic and cardiovascular surgery (Elsevier)
  • The Lancet Diabetes & endocrinology (Elsevier)
  • Postgraduate medical journal (BMJ)
  • Regional anesthesia & pain management (BMJ)
  • Rheumatology (OUP)
  • Schizophrenia bulletin (OUP)
  • Seminars in fetal and neonatal medicine (Elsevier)
  • Sleep (OUP)
  • Thorax (BMJ)